46th Annual Arthur H. Merritt Memorial Lectureship: Inflammation, Periodontitis and the Link to Systemic Diseases
Event on 2017-08-05 07:30:00
46th Annual Arthur H. Merritt Memorial Lectureship Inflammation, Periodontitis and the Link to Systemic Diseases Course Summary: Periodontitis is an infectious inflammatory disease; that is, a disease initiated by bacteria that has inflammatory destruction of tissues at the heart of its pathogenesis. Uncontrolled inflammation in infectious inflammatory diseases results from over-active stimulation and a failure to resolve inflammation. Resolution of inflammation is an active process mediated by endogenously produced lipid molecules that orchestrate a return to tissue homeostasis. These resolving molecules, called lipoxins and resolvins, are eicosanoids, the same class of molecule as prostaglandins and leukotrienes that actively regulate the resolution of acute inflammation. These small lipid molecules act through specific receptors on inflammatory cells. Lipoxins and resolvins have been shown to have significant impact in inflammatory diseases, such as periodontitis, type 2 diabetes and cardiovascular diseases. The new understanding of active resolution of inflammation has the potential to completely change how we approach periodontal therapy. Lipoxins and resolvins have been demonstrated to promote regeneration of bone lost to disease and to prevent inflammatory bone loss in animals. The potential for therapeutic benefit of lipoxins and resolvins in clinical periodontal regeneration is being examined. In addition to the emergence of new surgical and non-surgical, medical therapies for periodontal diseases, recent studies have suggested a relationship between oral infection, in particular periodontal disease, and systemic diseases. Epidemiologic studies have implicated periodontal disease as a risk factor for the development of cardiovascular disease and stroke, and a risk factor for pre-term low birth weight babies in pregnant women. In addition, studies in diabetics have revealed that untreated periodontal disease can lead to diabetic complications and have a direct impact on glycemic control. As our understanding of pathways of inflammation has matured, a better understanding of the molecular basis of inflammation has emerged. This presentation will review inflammation in the context of periodontal disease and its treatment, including regeneration, and the risk for systemic disease. The strengths and weaknesses of studies reported on these topics will be examined. The potential for modification of resolution pathways for the prevention and treatment of periodontal diseases will be discussed in detail. More importantly, the potential, as well as real, associations between periodontal diseases and systemic diseases underline the importance of proper diagnosis and treatment of these extremely common oral diseases. In this lecture, the rationale for additional periodontal medical approaches will be presented and the potential benefits to systemic health will be explored. Course Presenter: Thomas Van Dyke, D.M.D., Ph.D., is Vice President for Clinical and Translational Research, and Director of the Center for Clinical and Translational Research at the Forsyth Institute in Cambridge, MA. He received his D.D.S. (1973) from Case Western Reserve University; M.S. (1979) from SUNY at Buffalo in Oral Sciences; Periodontics Certificate (1980) from SUNY at Buffalo, and his Ph.D. (1982) from SUNY at Buffalo in Oral Biology. Dr. Van Dyke received the Balint Orban Memorial Prize for Research in Periodontology (1981). He is a Diplomate of the American Board of Periodontology (1989), and he received the IADR Award for Basic Research in Periodontology in 2001, the Norton Ross Award for Excellence in Clinical Research in 2002, and the William J. Gies Periodontology Award in 2008. He serves on the editorial boards of Infection and Immunity, Journal of Periodontology, Journal of Periodontal Research, among others, and he has edited two volumes of Periodontology 2000. He served as President of the International Association of Periodontology (1997-1999). Dr. Van Dyke has published 330+ original articles, and numerous abstracts and book chapters. He is a member of the American/International Association of Dental Research; American Academy of Periodontology; International Academy of Periodontology, American Association for the Advancement of Science, American Society of Microbiology, IADR Periodontal Research Group, American Dental Association, and American Association of Immunologists. His research interests are the structural and functional relationship of abnormalities of the inflammatory process with focus on phagocytic cells and microorganisms, in the etiology and pathogenesis of periodontal and other infectious inflammatory diseases. Dr. Van Dyke is also involved in clinical research and clinical trials focusing on drug treatment for periodontal disease, local delivery systems, and clinical trials of anti-plaque/anti-gingivitis agents, local anesthetics, regenerative periodontal therapies and early onset periodontitis. The remainder of his time is devoted to training of fellows and administration. Dr. Van Dyke is arguably the most renowned periodontal clinician scientist today. He is best known for his work on the pathogenesis of juvenile periodontal diseases, resolution of inflammation in neutrophil biology, and clinical research. Date: Saturday, August 5, 2017 Time: 7:30 am – 8:15 am – Registration/continental breakfast 8:15 am – 1:30 pm – Presentation Location: Beasley Auditorium, Baylor University Medical Center Questions: Please contact: DRoberts@tamhsc.edu or call 1-214-828-8140 Credit: 5.25 Hours Lecture AGD Codes: 490 Periodontics Continental breakfast/Late Morning refreshments Course Topics and Objectives: Review the relationship between inflammation and bone loss in periodontitis Discuss the data relating to the mechanism of action of periodontal regeneration Discuss potential modifications of treatment regimens for the patient with periodontitis in need of regenerative therapy Review the relationship between periodontitis and systemic disease Discuss the data relating to the mechanism of action of the periodontitis/systemic interaction Discuss potential modifications of treatment regimens for the patient with periodontitis and complicating systemic disease. Arthur H. Merritt, D.D.S. (1870- 1961) was one of the early pioneers in periodontics. In his later years, he was known as the “Dean of Periodontists.” His office was located on 5th Avenue in New York for many years. Dr. Merritt was one of the organizers of the American Academy of Periodontology and was very proud of the fact that he had attended every meeting but one, since its organization. In 1925 he served as President of the Academy. He was author of one of the first textbooks on periodontology and wrote many articles that have been published in that field. He taught periodontics at New York University School of Dentistry. Dr. Merritt was the first Diplomate of the American Board of Periodontology and served on the Board for several years. He received the Fauchard Medal in 1932, awarded by Dental Survey for Advancing the Field of Preventive Dentistry. Dr. Merritt visited Texas A&M College of Dentistry annually for many years and was a strong supporter of the Texas A&M training concept. The ARTHUR H. MERRITT MEMORIAL LECTURESHIP in Periodontics was established at Texas A&M College of Dentistry in December 1971. This lectureship in 2017 marks the 46th annual memorial lectureship. Because of the thoughtfulness and generosity of Dr. and Mrs. Merritt, graduate and undergraduate students of the college and members of the Southwest Society of Periodontists are privileged to share in the wisdom and knowledge of an outstanding lecturer in the field of periodontology. The Arthur H. Merritt Lecturers 1972 Dr. Helmut Zander * 1994 Dr. William Becker 1973 Dr. Donald A. Kerr* 1995 Dr. Michael G. Newman 1974 Dr. John F. Prichard* 1996 Dr. Jay S. Seibert* 1975 Dr. Sigurd P. Ramfjord* 1997 Prof. Giovan Paolo Pini Prato 1976 Dr. S. Sigmund Stahl* 1998 Dr. J. Gary Maynard* 1977 Dr. Harald Löe* 1999 Dr. Niklaus Lang 1978 Dr. Sigmund S. Socransky* 2000 Dr. Dennis P. Tarnow 1979 Dr. Jan T. Lindhe 2001 Dr. Sebastian G. Ciancio 1980 Dr. Robert G. Schallhorn 2002 Dr. Maurizio S. Tonetti 1981 Dr. Knut A. Selvig 2003 Dr. Louis F. Rose 1982 Dr. Timothy J. O'Leary* 2004 Dr. Gary C. Armitage 1983 Dr. William K. Bottomley* 2005 Dr. Terry D. Rees 1984 Dr. Robert J. Genco 2006 Dr. Daniel Buser 1985 Dr. Max A. Listgarten 2007 Dr. Raymond A. Yukna 1986 Dr. Sture A. Nyman* 2008 Dr. Brian A. Mealey 1987 Dr. Roy C. Page 2009 Dr. Edward P. Allen 1988 Dr. Burton Langer 2010 Dr. Michael K. McGuire 1989 Dr. Alan M. Polson 2011 Dr. Maurice A. Salama 1990 Dr. Myron Nevins 2012 Dr. Stuart J. Froum 1991 Dr. Gerald M. Bowers 2013 Dr. Anton Sculean 1992 Dr. Jens J. Pindborg* 2014 Dr. Hom-Lay Wang 1993 Dr. Ray C. Williams 2015 Dr. Henry Greenwell 2016 * Deceased Course Organizers: Dr. Thomas Diekwisch: Department Chair, Periodontics Born in Bielefeld, Germany, Dr. Diekwisch holds degrees in dental medicine (1986, D.M.D.), Anatomy (1988, Ph.D. with "summa cum laude"), and philosophy (2005, Ph.D. with “magna cum laude”), all from the Philipps-University of Marburg/FRG. From 1986-1990, Dr. Diekwisch worked as a lecturer, clinical instructor, and research associate in the Departments of Anatomy and Periodontics at the Philipps-University. After postdoctoral training at the University of Southern California he joined the faculty of Texas A&M College of Dentistry in Dallas/TX in 1994, where he created an award-winning community science education outreach program entitled “Habitat for Science”. In 2001, Dr. Diekwisch was recruited to the University of Illinois at Chicago to become the first Director of the Brodie Laboratory for Craniofacial Genetics and the Allan G. Brodie Endowed Chair. Two years later, he was appointed Professor and Head of the Department of Oral Biology at UIC. His research areas include stem cells, tissue engineering, chromatin and epigenetics, development and evolution of teeth, tooth movement, and history of science. Dr. Diekwisch is known for the first successful stem cell-based engineering of a complete periodontal ligament and for establishing the role of amelogenin self-assembly in enamel crystal growth. He has also discovered a chromatin factor, CP27 that is essential for cell growth and survival. In 2009, Dr. Diekwisch became an honorary professor at Jilin University in Changchun, China. In 2014, Diekwisch returned to Texas A&M College of Dentistry as the Director of the Center for Craniofacial Research and Diagnosis and Chair of the Department of Periodontics. In this new role, Diekwisch is applying his work on tissue regeneration, epigenetics, and craniofacial biology in a clinical setting to create a new environment that integrates Texas A&M's strengths in clinical dentistry and basic sciences. TAMCOD Office of CE Registration Information, Certifications & Cancellation/Refund policy: Texas A&M University College of Dentistry is an ADA CERP Recognized Provider. QUESTIONS: Please feel free to call us at 1-214-828-8238. For quickly response please email your questions through the online registration website ADA CERP is a service of the American Dental Association to assist dental professionals in identifying quality providers of continuing dental education. ADA CERP does not approve or endorse individual courses or instructors, nor does it imply acceptance of credit hours by boards of dentistry. Concerns or complaints about a CE provider may be directed to the provider or to ADA CERP at www.ada.org/cerp. Continuing education credits issued for participation in the CE activity may not apply toward license renewal in all states/provinces. It is the responsibility of each participant to verify the requirements of his/her state/provincial licensing board(s). CONFIRMATIONS: Will be sent by e-mailto the official email address provided by the attendee to the registration website. Exact email is necessary REGISTRATION CANCELLATION:Tuition is refundable if a course is canceled by the Office of CE. A fee will be assessed for any course cancellation. All payments by check or cash are deposited into the Texas A&M account and CANNOT be refunded. “No Shows” for a course forfeit all tuition. Confirm notification of cancellation by e-mail.The CE Office cannot be held responsible for a non-refundable airline ticket.
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